中中 网站
"Hominis OMICRON est prope ad quod temporis influenza" et "omicron est significantly minus morbifica quam Delta." ...... nuper, multum nuntium de virum de novo coronam mutant iactabantur omicron est diffusa in Penitus.
Immo cum cessum ex omicro mutant iactabantur in November MMXXI et ejus global invaluisset, investigationis et disputationem in viru et transmissio continued unabed. Quid est current virum profile de omicron? Quid est investigationis dicunt de ea?
Variis Laboratory Studies: Not Minus virulentum
In facto, ut mane Ianuarii MMXXII, a studio a University of Hong Kong Li Ka Singh Faculty of Medicinae inventa quod omicron (b.1.1.529) potest esse minus pathogenic ad originale iactabantur et aliis mutant modos comparari.
Inventus est inventa quod in omni mutant iactabantur in inhabitabilis in usura Transmembrane Serine protease (TMPRSS2), dum TMPRSS2 poterat facilitate virilli tumultuantur exercitum cellulis a cliff dapibus in novo coronavirus. Simul inquisitores observari omicron replicatione fuit significantly reducitur in humano cellula lineas calu3 et caco2.
Image Source Internet
In K18-Hade2 mus exemplar, omicron replicatione reducitur in utroque superioribus et inferioribus respiratorii tractus mures comparari ad originale iactabantur et delta mutant et alpha et Membra et Delta Mutantium.
Ergo inquisitores concludi omicron replicatione et morbificate reducuntur in mures.
Image Source Internet
In XVI Maii MMXXII, naturae published a chartam per Yoshihiro Kawaoka, a ducens virologist ex University of Tokyo et University of Wisconsin, confirmans primum in an animalibus, quam prior originali.
In investigatores lectus vivere ba.2 virus separatim in Iaponia ad infect K18-Hade2 mures et hamsters et invenit, post infectio in pulmone et nasus, quam originali et ba.1 infectione (P <0.0001.)
Hoc aurum vexillum effectus confirmat quod omicron est quidem minus virulenta quam originali fera genus. In contrarium non fuit significant differentia in virales titres in pulmone et naso animalis exempla sequentibus Ba.2 et Ba.1 infectiones.
Image Source Internet
PCR Viral onus assays ostendit quod tam ba.2 et Ba.1 infectis mures habuit inferioribus virales onerat in pulmone et nasus quam originale novum coronam iactabantur, praecipue in pulmone (P <0.0001).
Similia ad praecessi in mures, in virales titres deprehenditur in nasum et pulmones Ba.2 et Ba.1 infectis hamsters sunt inferiores quam originali iactabantur, in inoculatione et leviter in naso et in ba.2 infectae in infectione non develop pulmo.
Fuerunt adhuc invenitur quod originale fervat, Ba.2 et Ba.1, laeded crucem-neutralization de Sera sequenti contagione - consistent cum ea quae sunt in real-mundi homines, cum infici cum diversis novi coronam mutant.
Image Source Internet
Verus-Mundi data: Omicron est minus verisimile ad causam gravis morbo
Plures ex supra studiis descripsit redactis virum omicron in laboratorium animal exempla, sed idem verum in realem mundi?
De VII Iunii MMXXII, qui edidit in relatione perpendendis differentia in severitatem populi infectis in omicron (b.1.1.529) epidemiam comparari ad Delta Pandemic.
Report includitur 16.749 nova coronarius inpatients ab omnibus provinciis de South Africa, inter 16,749 ex Delta pestis (2021/8/2 ad 2021/10/3) et 17.693 ab Omicrons epidermic (2021/11/15 ad 2022/2/16). Et aegris fuerunt quoque classificatis ut severus, gravi et non-gravis.
Critica: accepit incursio VENTILATIO, aut oxygeni et altus-fluxus transnasal oxygeni, aut extracorporeal membrana oxygenation (ECMO), aut admissionem ad ICU in hospitalization.
-severe (Seruis): accepit oxygeni per hospitalization
-non-severus, si non ex supra conditionibus occurrit, patientes estote non-gravibus.
In notitia ostendit quod in Delta Group, 49.2% erant gravi, 7,7% erant discrimine et XXVIII% of omnes hospitalized Delta inficiuntur aegris mortuus est, cum per omicron Group et XV% de omnibus hospitalized in infecta et XV% of omnes hospitalized inficitur aegroti et in omnibus hospitalized aegris et in omnibus hospitalized aegris et infici et XV% in infectam aegroti sunt, 3.7 infici et in omnibus hospitalized aegris et in omnibus hospitalized aegris et aegris et in omnibus hospitalized aegris et aegris et in omnibus hospitalized aegris et aegris et inficitur et in omnibus hospitalized aegris et aegris et in omnibus hospitalized aegris et aegris et infici et in omnibus hospitalized aegris et aegris est. Etiam, in media longitudinem manere fuit VII diebus in Delta coetus comparari ad VI diebus in omicron coetus.
In addition, the report analysed the influencing factors of age, gender, vaccination status and comorbidities and concluded that Omicron (B.1.1.529) was associated with a lower probability of serious and critical illness (95% CI: 0.41 to 0.46; p<0.001) and a lower risk of in-hospital death (95% CI: 0.59 to 0.65; p<0.001).
Image Source Internet
Nam alia subtypes de omicron, ulteriores studia etiam resolvitur suos in detail.
A Cohors Studio ex Nova Anglia Analyzed (XX) DCCLXX casibus Delta, (LII) DCV casibus de omicron b.1.1.529 et (XXIX) DCCCXL casibus de omicroni Ba.2, et invenit, quod proportio mors est 0.7% ad Ba.2% 0.4. Post adjusting ad confundentes factores, studium concludi quod periculum mortis fuit significantly inferiori ad Ba.2 comparari utrique Delta et B.1.1.529.
Image Source Internet
Alius studio a South Africa aestimatus periculum hospitalization et periculo gravi exitus Delta, Ba.1, Ba.2 et Ba.4 / Ba.5. In eventus ostendit quod de 98.710 nuper infici aegris includitur in analysis, MMMDCCCXXV (3.9%) admissus ad hospitalis, quorum MCCLXXVI (33.4%) developed gravibus morbus.
Inter eos infici cum diversis mutationibus, 57.7% of Delta-infectis aegris developed gravibus morbo (97/168), comparari ad 33.7% of Ba.1-inficiuntur aegris (990/637), 26.2% of Ba.2 (167/637) et 26.2 de Ba.2 (22/80). Multivariate analysis ostendit quod probabilitas developing gravi morbo inter ea infici Delta> Ba.1> Ba.2, dum probabilitatem developing gravi morbo inter eos infici Ba.2.
Redegit virum, sed vigilantia opus
Laboratory studiis et realis notitia ex pluribus terris ostensum est quod omicron et subtypes sunt minus virulos et minus verisimile ad causam gravi morbum quam originali iactabantur et aliis mutant modos.
However, a review article in the January 2022 issue of The Lancet, entitled 'Milder but not mild', noted that although Omicron infection accounted for 21% of hospital admissions in the younger South African population, the proportion of outbreaks causing severe disease was likely to increase in populations with different levels of infection and different levels of vaccination. (Nihilominus, in hoc fere iuvenes South African population, XXI% of hospitalized aegris infici cum Sars-Cov-II omicron variante habebat gravibus orci et inferioribus in motum in populis et causa substantial et inferioribus et infectionum, derived et Vaccine, et inferioribus.)
In fine autem praedictorum qui fama, in quadrigis attendendum quod non obstante redactis virum prior iactabantur, fere tertiam partem hospitalized omicron (b.1.1.529 in senes, immunocompromised et mortalitatem et in senes, immunococomis et in variis et mortalitatem, et in senes, immunococinorum et non unvaccinated populationibus. (We would also like to caution that our analysis should not be seen as supportive of the 'mild' variant narrative. Nearly a third of the hospitalized Omicron patients developed severe disease and 15% died; numbers which are not insignificant……Among vulnerable populations, ie patients at the extremes of age, in populations with high comorbid burden, in frail patients and among the unvaccinated, COVID-19 (all VOCs) continues ad substantial Morbidity et mortalitatis.)
Previous data from Omicron when it triggered the fifth wave of the pandemic in Hong Kong showed that as of 4 May 2022, there were 9115 deaths out of 1192765 newly crowned cases during the fifth wave (a crude mortality rate of 0.76%) and a crude mortality rate of 2.70% for people over 60 years of age (about 19.30% of this age group were unvaccinated).
In contrarium, solum II% of New Zealanders super LX annos aetatis sunt unvaccinated, quae valde connectuntur cum humilis crudi mortalitatis rate of 0.07% ad novum coronalem pestilentiam.
In alia manu, dum est saepe arguitur, quod Novumcastle potest facti temporis, Endemica morbus in futurum, sunt academicorum peritis qui accipit diversum visum.
Tres scientists ex University of Oxford et Europaeae Unionis Community Research Centre credere quod inferioris severitatem omicron ut simpliciter esse accidit, et continuata celeri antigenic evolution (antigenic evolution) ut producat de novo variants.
Dissimilis immunes effugium et transmissibiliter, quae sunt fortis evolutionis pressura, vir fortis solet iustus a 'per-productum, de evolutione. Viruses evolve ad maximize eorum facultatem ad propagationem, et hoc etiam ad augmentum in viruundence. Exempli gratia, per augendae virales onus ad facilitate tradenda, potest adhuc faciam magis gravibus morbus.
Not only that, but virulence will also cause very limited harm during the spread of a virus if the symptoms brought on by the virus appear mainly later in the infection – as in the case of influenza viruses, HIV and hepatitis C viruses, to name a few, which have plenty of time to spread before causing serious consequences.
Image Source Internet
In tali adiunctis, ut sit difficile praedicere trend of novus coronam mutant iactabantur a inferioribus virusterce omicron, sed evangelizavit periculo gravibus morbum et mors in omnibus mutant rates manet in hoc momenti ad pugnam in hac re manet.
Acknowledgements: Hic articulus est professionally recensuit ab Panpan Zhou, PhD, Tsinghua University School of Medicine et postdoctoral conservis, Scripps Research Institute, USA, USA
Omicron auto-testing antigen Reagent domi
Post tempus: Dec-08-2022
Privacy Occasus